Hospital Practices and Research

Abstract Background: Platelets/Lymphocyte Ratio (PLR) has been investigated not only in hematological diseases but also in clinical conditions involving almost all organs and systems including inflammatory, neoplastic, and cardiovascular diseases.
Objectives: This study was planned to perform an analysis of the studies on PLR through the PubMed database, to measure the impact of the relevant studies on the diagnosis of diseases.
Methods: This analysis was performed on 16.01.2021 by searching with the word group "platelet lymphocyte ratio", "platelet lymphocyte ratio" in the PubMed database.
Results: The study included 723 articles, of which 580 (80.2%) were retrospective. It was determined that 420 (58.1%) of the studies were conducted by a single clinical department, 55.6% (n=402) were indexed in SCI/SCI-E index, 56.7% (n=410) were Open Access, and 58.8% (n=425) had significant results related to the clinical condition studied. Most publications were from Turkey (n=239, 33.1%), China (n=211, 29.2%), and Japan (n=55, 7.6%).
Conclusion: The majority of the analyzed studies were retrospective, and were SCI/SCI-E indexed. Their role in malignancy diagnoses was evaluated the most. A total of 59 different clinical conditions were evaluated and "platelet lymphocyte ratio" was found useful in the diagnosis of relevant clinical conditions in 58.8% of the studies. PLR is a value that is significantly associated with the diagnosis and prognosis of many diseases and can be obtained by a simple calculation from a complete blood count.