TY - JOUR ID - 82683 TI - Sporadic Burkitt Lymphoma: A Case Report JO - Hospital Practices and Research JA - HPR LA - en SN - 2476-390X AU - Vargas Flores, Edgar AU - Avitia Raygoza, Claudia Leticia AU - Hernández Castañeda, Daniel AU - Sánchez Garza, Jorge Arturo AU - Quintana Cortéz, Juan Carlos AD - General Surgery Department, Hospital General de Zona 5, Instituto Mexicano del Seguro Social, Sonora, Mexico AD - Hematology Department, Hospital General de Zona 5, Instituto Mexicano del Seguro Social, Sonora, Mexico AD - Pathology Department, Hospital General de Zona 5, Instituto Mexicano del Seguro Social, Sonora, Mexico Y1 - 2019 PY - 2019 VL - 4 IS - 1 SP - 42 EP - 44 KW - Lymphoma KW - Burkitt Lymphoma KW - Hematology DO - 10.15171/hpr.2019.07 N2 - Introduction: Burkitt lymphoma is an aggressive subtype of Hodgkin lymphoma with a doubling time of 25 hours. It is characterized by a MYC gene coding alteration which results from a translocation of chromosome 8 on the MYC gene locus and immunoglobulin heavy-chain locus (IGH) on chromosome 14. Even though HIV infection is associated to an increased risk of Burkitt lymphoma, these type of malignancies are EBV-negative cases. Sporadic type Burkitt lymphoma is a rare clinical entity. Case Presentation: A 48-year-old female without any past medical history presented with a chief complaint of mild abdominal pain of 6 months duration located at the epigastrium which was not related to food ingestion. Nausea or vomiting were neither reported. She noted an acute increased abdominal pain over the last 4 hours before presentation, with irradiation to the right lower quadrant. She denied any Fever, night sweats and weight loss. She also reported hypermenorrhea in the last 6 months. During the physical examination, a palpable mass with 10 cm in diameter was found on right lower quadrant. Conclusion: Sporadic Burkitt lymphoma is one of the rarest hematologic malignancies. The increased tumor size may be more than enough to show clinical or biochemical abnormalities such as serum lactate dehydrogenase (LDH) increased and tumor lysis. UR - https://www.jhpr.ir/article_82683.html L1 - https://www.jhpr.ir/article_82683_8c7e6fb16e798ed16f529b354963c12e.pdf ER -