Baqiyatallah University of Medical Sciences Hospital Practices and Research 2476-390X 11 2 2026 06 01 Islamic Spiritual Therapy and Improvement of Mental Health in Hospital Nurses: A Quasi-Experimental Study 893 899 248404 10.30491/hpr.2026.502464.1467 EN Mojtaba Gharabaghi Human Genetics Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran 0009-0007-6222-2708 Mohammad Ali Akhavan Department of Quran and Science, Quran and Hadith Higher Education Complex, Al-Mustafa International University, Qom, Iran Fatemeh Agha Sheikh Hassan Department of Persian and Islamic Traditional Medicine, Ibn Sina International College, Georgia Fatemeh Mehrabi Department of Complementary Medicine with a Focus on Persian and Islamic Traditional Medicine, Ibn Sina University, Georgia Journal Article 2025 01 26 <strong>Background:</strong> Hospital nurses face psychological challenges and occupational burnout due to the demanding nature of their profession. Variables such as resilience, openness to experience, identity styles, and expansion of spiritual experiences have been shown to reduce these problems, but have mainly been studied in non-Muslim societies using non-Islamic approaches. This study addresses this gap by examining the effectiveness of Islamic spiritual therapy on these variables in hospital nurses.<br><strong>Objectives:</strong> To investigate the effectiveness of Islamic spiritual therapy on resilience, openness to experience, identity styles, and expansion of spiritual experience in hospital nurses.<br><strong>Methods:</strong> This was a semi-experimental study with a pre-test-post-test design and a control group. The sample consisted of 30 nurses working in public hospitals in Tehran, Iran, selected using convenience sampling and randomly assigned to experimental and control groups. The experimental group received 10 sessions of 90-minute Islamic spiritual therapy, while the control group received no intervention. Data were collected using the Connor and Davidson Resilience Scale (CD-RISC), the Revised NEO Personality Inventory (NEOPI-R) for openness to experience, the Berzonsky Identity Styles Questionnaire (ISI-6G), and the Underwood and Teresi Daily Spiritual Experiences Scale (DSES). Data were analyzed using analysis of covariance (ANCOVA).<br><strong>Results: </strong>The results showed that Islamic spiritual therapy had a significant effect on resilience, openness to experience, identity styles (informational, normative, avoidant/confused, and commitment), and the expansion of spiritual experience in hospital nurses (P < 0.05).<br><strong>Conclusion:</strong> Islamic spiritual therapy enhances resilience, openness to experience, identity styles, and spiritual experiences in hospital nurses. It can reduce burnout and promote holistic (physical-psychological-spiritual) care in hospital settings. Future research should include larger sample sizes and follow-up assessments. https://www.jhpr.ir/article_248404_88ff794c045ad7ac7180c243bfbe4907.pdf