Keywords = Depression

Enhancing Cognitive-Attentional Functioning and Life Expectancy Hope through Acceptance and Commitment Therapy in Depressed Youth

Volume 10, Issue 3, Summer 2025, Pages 719-725

https://doi.org/10.30491/hpr.2025.524219.1493

Sahar Amiri, Fatemeh Khosravi Saleh Baberi, Elham Hashemi Hendikosh, Masoumeh Jalili

Abstract Background: The pervasive impact of depression on cognitive-attentional processes and future hope in young individuals underscores the critical need to investigate targeted interventions. Objectives: This study aimed to evaluate the effectiveness of Acceptance and Commitment Therapy (ACT) in improving Cognitive-Attentional Syndrome (CAS) and enhancing hope for the future in young adults experiencing depression. Methods: A quasi-experimental design was employed with a pre-test/post-test control group. The target population consisted of young adults aged 18-35 years diagnosed with depression, who presented for services at psychology and counseling centers in Ahvaz during 2021. A convenience sample of 40 eligible individuals was recruited and randomized into two groups: an experimental group and a control group, each comprising 20 participants. Data were collected using the Cognitive Attentional Syndrome Questionnaire (CAS-Q) and the Adult Hope Scale (AHS). The experimental group underwent eight weekly 90-minute sessions of ACT, while the control group was placed on a waitlist with no intervention. Analysis of Covariance (ANCOVA) was employed to analyze the collected data. Results: A statistically significant reduction was found in CAS scores (F=255.28, P<0.001, η=0.83) and a significant increase in hope scores (F=296.46, P<0.001, η=0.93) among young adults with depression in the post-intervention assessment within the ACT group, relative to the control group. These findings indicate that ACT is an effective treatment for mitigating maladaptive cognitive-attentional patterns and cultivating greater hope for the future in this demographic. Conclusion: This study provides robust evidence for the efficacy of ACT in reducing CAS and enhancing dispositional hope in young adults with depression. These findings suggest ACT’s potential as a scalable clinical intervention to address core psychological processes and improve long-term mental health outcomes.

A Review of the Role of Interleukin-2 in the Pathophysiology of Major Depressive Disorder in Hospitalized Patients

Volume 6, Issue 3, Summer 2021, Pages 85-92

https://doi.org/10.34172/hpr.2021.17

Seyed Alireza Seyed Ebrahimi, Elham Karamian, Zahra Sadat Goli, Leila Sadat Mirseifi

Abstract Background: Hospitalization due to any reason or medical condition is associated with fear, anxiety, and depression. Psychological and physiological factors have a significant impact on hospitalization outcomes.
Objectives: Given the functional importance of inflammatory cytokines and studies in previous studies on the relationship between inflammatory cytokines and major depressive disorder, we will focus more on studies on the role of interleukin 2 (IL-2) in the pathophysiology of major depressive disorder in hospitalized patients.
Methods: We used PubMed, Scopus, and Elsevier databases to search for articles from 1999 to 2021, emphasizing the studies of the last five years.
Results: In general, there was no consistent pattern in the observed relationships between cytokine concentrations or changes and clinical signs of significant depression. IL-2 and IL, two receptors in the body, play an essential role in the treatment and the pathophysiology of depression and major depression.
Conclusion: Finally, it can be concluded that hospitalization generally exposes the patient to inflammation. Studies show an increased risk of inflammation following hospitalization of patients, and many studies confirm the association of major depression with inflammatory cytokines and, more concentrated, IL-2.

Comparison of Depression and Quality of Life after Coronary Artery Bypass Graft Surgery in Patients With and Without Type D Personalities

Volume 6, Issue 3, Summer 2021, Pages 105-111

https://doi.org/10.34172/hpr.2021.20

Shahriar Mali, Nahid Khajehmougahi, Somaye Hajatnia, Aida Farsham, Elham Hasibi, Reza Bidaki

Abstract Background: Recently, some studies have investigated type D personality as a critical factor in developing depression and reducing the quality of life.
Objectives: This study aimed to compare depression and quality of life after coronary artery bypass graft surgery in patients with and without type D personalities.
Methods: Sixty-nine participants who underwent coronary artery bypass grafting at Imam Khomeini hospital, Ahvaz, Iran, referred to the cardiac surgery clinic for their first visit (1 to 1.5 months after surgery) were included in the study. All participants completed the World Health Organization Quality of Life questionnaire, type D personality scale, and Beck’s Depression Inventory. Finally, depression and quality of life were compared in two groups with and without type D personalities using ANOVA and correlation tests.
Results: The two groups were significantly different in depression and quality of life scores after coronary artery bypass graft surgery. Depression and quality of life impairment were higher in participants with type D personality. There was no significant relationship between depression and quality of life with age, gender, and occupation in participants with type D personality.
Conclusion: Depression and quality of life were higher in patients with type D personality after coronary artery bypass graft surgery than patients without type D personality. Episodic screening of these patients can prevent future somatic and psychological problems.

Correlation Between Suicide Attempts and a History of Childhood Abuse in Adults Referring to the Toxicity Emergency Units of Yazd City, Iran

Volume 5, Issue 1, Winter 2020, Pages 24-27

https://doi.org/10.34172/hpr.2020.05

Elham Bazdar, Bonnie Bozorg, Fatemeh Ayoobi, Hamid Owliae, Reza Bidaki

Abstract Background: Child abuse is defined as any act or omission which causes physical or psychological harassment and lasting effects on children. Injuries resulting from child abuse are widespread, and this trauma can lead to psychological problems in adulthood.
Objective: The aim of this study was to investigate the correlation between a history of child abuse and suicide attempts.
Methods: In this case-control and retrospective study, patients admitted in 2016 to the toxicity emergency center in Yazd city, Iran, with symptoms of attempted suicide and patients of other conditions were recruited. Participants in the control and case groups were matched for age, gender, marital status, and place of residence. Each patient was given a questionnaire to collect information on demographics, history of suicide attempt or suicide in other members of the family, and history of child abuse (self-report scale) which investigated five aspects of childhood abuse (sexual, physical, neglect, lack of nutrition, and emotional neglect).
Results: The chi-square test and t test were used in the analysis. Mean severity rates of physical, sexual, neglect, nutrition, and emotional child abuse were 8.49, 6.42, 10.4, 6.43, and 9.62, respectively, for the case group and 7.89, 5.52, 7.88, 5.92, and 8.52, respectively, for the control group.
Conclusion: Statistical analysis revealed that except for nutritional abuse cases, the incidence rates of all other aspects of child abuse were significantly higher among cases than in the control group. The results of this study showed that a history of child abuse, especially sexual and emotional types, are correlated with the incidence of attempted suicide.

Comparing Anxiety, Depression, and Stress in Consanguineous Versus Non-Consanguineous Parents of Children With Deafness in Baqiyatallah Hospital’s Cochlear Implant Center From 2007 to 2009

Volume 3, Issue 3, Summer 2018, Pages 85-89

https://doi.org/10.15171/hpr.2018.19

Sima Noohi, Mohammad Ghalamfarsa, Esmat Davoudi Monfared

Abstract Background: The birth of a child with a hearing disability is a stressful event in the family. Since consanguineous marriages are associated with the incidence of congenital hearing loss, it is expected that such parents will experience greater psychological problems.
Objective: The current study investigated and compared anxiety, depression, and stress in parents of children with severe hearing loss who have undergone cochlear implantation with a focus on the relation between parents (consanguineous vs. non-consanguineous).
Methods: This cross-sectional study was conducted on all 180 couples (360 individuals) who had become parents and attended Baqiyatallah hospital’s Cochlear Implant Center from 2007 to 2009. The participants included two groups of consanguineous (125 couples) and non-consanguineous (55 couples) parents. After providing consent to participate in this study, the participants completed the short form of the Depression and Anxiety and Stress Scale questionnaire (DASS-21). Data analysis was done using SPSS 17 and t test.
Results: The participating parents had high levels of depression, anxiety, and stress. Depression and anxiety were significantly higher among the consanguineous parents (P=0.001 and P=0.005, respectively). However, stress levels were not significantly different between the 2 groups. Moreover, compared to the fathers, the mothers had higher levels of depression, anxiety, and stress (P<0.05).
Conclusion: Based on these findings, it may be concluded that the birth of a child with hearing loss can be the source of psychological problems in parents, particularly in consanguineous parents. Furthermore, mothers are more psychologically vulnerable than fathers.