@article { author = {Gurung, Brikshya and Maheshwari, Saurabh and Grewal, Darshan Singh and Regmi, Pratik and Khadka, Ajay}, title = {Transfusion-Related Hemochromatosis Involving Pituitary Gland in a Patient of Beta-Thalassemia Major}, journal = {Hospital Practices and Research}, volume = {7}, number = {1}, pages = {37-40}, year = {2022}, publisher = {Baqiyatallah University of Medical Sciences}, issn = {2476-390X}, eissn = {2476-3918}, doi = {10.34172/hpr.2022.08}, abstract = {Introduction: Hemochromatosis of the pituitary gland is a form of iron overload disease which occurs in different clinical conditions related to multiple blood transfusions.Case Presentation: We present a case of secondary hemochromatosis involving the pituitary gland and choroid plexus in an eight-year-old female with imaging findings and a review of the relevant literature. Our patient has had a history of cessation of growth in height for the last 1 year. She was diagnosed with a thalassemia major at the age of 6 months. She has been on regular blood transfusions since then. Magnetic resonance imaging (MRI) revealed evidence of iron deposition in the pituitary gland.Conclusion: This diagnosis should be suspected on clinical presentation and history of multiple blood transfusions. It can be confirmed based on characteristic imaging findings. The patient should be strictly monitored with serum iron levels, and a tailored iron chelation therapy should be initiated.}, keywords = {Hemochromatosis,Blood transfusion,Thalassemia,Chelation Therapy,MRI scans}, url = {https://www.jhpr.ir/article_143456.html}, eprint = {https://www.jhpr.ir/article_143456_27e7ea56e65e64d5d218fee5c29b73cc.pdf} }