TY - JOUR ID - 82764 TI - Improvement of Psychological Symptoms After Replacement Therapy With Levothyroxine in Hypothyroidism: A Report of 2 Cases JO - Hospital Practices and Research JA - HPR LA - en SN - 2476-390X AU - Bidaki, Reza AU - Tavana, Bita AU - Hosseini, Shima AU - Neshati, Negar AU - Babaei Zarch, Mojtaba AD - Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AD - Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran AD - Kharazmi University, Tehran, Iran AD - School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Y1 - 2019 PY - 2019 VL - 4 IS - 1 SP - 39 EP - 41 KW - Hypothyroidism KW - Persecutory Delusion KW - Psychological Disturbance DO - 10.15171/hpr.2019.06 N2 -   Introduction: Hypothyroidism is a common disorder of the endocrine system in which the production of thyroid hormones is inadequate. In addition to various physical manifestations, patients who suffer from hypothyroidism may also present with psychological problems, as described in previous studies. Case Presentation: Herein, the reports of 2 patients who suffered from hypothyroidism and experienced improvement in their psychological symptoms after levothyroxine therapy are presented. The patients referred with depressive mood with psychotic features and psychomotor retardation. Treatment simultaneously with psychopharmacotherapy and hormone therapy was considered. Conclusion: Although hypothyroidism and depressive disorders are separate issues, hypothyroidism can induce depression and psychosis, and psychopharmacotherapy plus hormone therapy can be effective and boost treatment. UR - https://www.jhpr.ir/article_82764.html L1 - https://www.jhpr.ir/article_82764_16c9ce28ca3e1daca98775cf778ec926.pdf ER -