Baqiyatallah University of Medical Sciences Hospital Practices and Research 2476-390X 6 4 2021 12 01 Impact of Transcranial Direct Current Stimulation on Patients With Parkinson’s disease: A Report of 2 Cases 173 176 138567 10.34172/hpr.2021.32 EN Reza Bidaki Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 0000-0002-5482-9143 Hamid Mirhosseini Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 0000-0002-3505-109X Nahid Zare Shahid Sadoughi University of Medical Sciences, Yazd, Iran Journal Article 2020 11 02 <strong>Introduction: </strong>The motor function is associated with the activity of both the motor and prefrontal cortices. The efficacy of transcranial direct current stimulation (tDCS) over specific brain cortices has been examined in many psychiatric and neurologic disorders. This study aims to report the tDCS effects on two females of advanced age with idiopathic Parkinson’s disease (PD).<br /><strong>Case Presentation: </strong>We considered 50-minute sessions of bilateral primary motor cortices and left dorsolateral prefrontal cortex (DLPFC) anodal stimulation using tDCS with passive stretching exercises simultaneously for a total of 20 sessions in 7 weeks. Clinical signs and electroencephalography (EEG) waveform were assessed at distinct times. Both of the two patients showed improved motor function for a short time. EEG changes to some extent concerned clinical states.<br /><strong>Conclusion: </strong>It seems that tDCS can be an auxiliary treatment for motor dysfunction in PD; however, further studies must be carried out to prove the claim. https://www.jhpr.ir/article_138567_36bfe0e3663ac53458f5c52a212ee1f3.pdf