Baqiyatallah University of Medical Sciences Hospital Practices and Research 2476-390X 7 4 2022 12 12 A Retrospective Study: ABO and Rh Phenotype Blood Group Distribution Amongst Different Types of Craniosynostosis Patients 145 148 162748 10.34172/hpr.2022.28 EN Ali Riazi Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-8849-7677 Ali Abbasivand School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Alireza Arabi National Center for Health Insurance Research, Tehran, Iran Mehrdad Larry Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-0777-6421 Journal Article 2022 08 11 <strong>Background: </strong>Craniosynostosis refers to the premature fusion of cranial sutures. Premature closure can impair brain development and cognitive problems. Only available treatment of craniosynostosis is through surgical intervention which is associated with excessive blood loss.<br /><strong>Objectives:</strong> In this study, we investigate the prevalence of each ABO/Rh blood group amongst patients with different types of craniosynostosis.<br /><strong>Methods: </strong>We included 163 patients, under craniosynostosis treatment, in Imam Hossein children’s hospital at Isfahan, Iran. A retrospective analysis was performed and the frequency of blood groups as well as types of craniosynostosis were reported. Moreover, the connection between ABO/Rh blood groups and the types of craniosynostosis was examined by chi-square test.<br /><strong>Results:</strong> Of 163 cases reviewed; The majority of participants had blood group A positive (32.5%), followed by O positive (31.3%). The rest of the blood groups were reported in order: B positive (22.1%), B negative (4.9%), AB positive (4.3%), O negative (2.5%), A negative (1.8%), AB negative (0.6%). Also, the most common type of craniosynostosis was metopic (27%) and the other types were pansynostosis (23.9%), sagittal (21.5%), coronal (16.6%), multisuture (10.4%) and lambdoid (0.6%) respectively. Due to connection between ABO/Rh blood groups and the types of craniosynostosis, no significant relationship was observed.<br /><strong>Conclusion:</strong> Based on the results of the present study, it was found that the frequency of ABO blood groups in children with craniosynostosis can be different from the population of the same area. Also, the ratio of different types of craniosynostosis was different from previous data. https://www.jhpr.ir/article_162748_37263627a590918e3a0fcc250e5c87ba.pdf