Baqiyatallah University of Medical Sciences Hospital Practices and Research 2476-390X 10 3 2025 09 20 Disposable versus Reusable Medical Supplies: Balancing Safety, Sustainability, and Economics in Healthcare 695 696 230306 10.30491/hpr.2025.524305.1494 EN Neha Rai Nursing officer, Continuous Nursing Education & Transplant Coordinator, AIIMS Jodhpur, India 0000-0002-2110-1383 Journal Article 2025 05 17 The choice between disposable and reusable medical supplies remains a critical challenge in healthcare systems worldwide, particularly in low- and middle-income countries. While disposable items offer the advantage of infection prevention, they contribute significantly to biomedical waste and impose recurring financial burdens. Reusable supplies, on the other hand, present economic and environmental benefits but carry infection control risks if sterilization practices are inadequate. This paper explores the trade-offs between safety, sustainability, and cost in the context of Indian healthcare institutions, including experiences from apex institutes like AIIMS. Global trends, environmental implications, and emerging innovations in reprocessing technologies are also discussed. The findings support the need for a hybrid, risk-based strategy that optimizes both resource utilization and patient safety. Strengthening sterilization infrastructure, establishing national reuse protocols, and investing in low-cost innovations are recommended to balance the competing priorities of modern healthcare delivery. https://www.jhpr.ir/article_230306_ca7e51f99af5744f21fdae94c5cc9d57.pdf