Document Type : Original Article


1 Student of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

2 Medical Student, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Department of Neurosurgery, School of Medicine, Emam hosein Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.



Background: Craniosynostosis, defined as the premature fusion of the cranial sutures, which can causes impair brain development and cognitive problems.
Objective: The purpose of this study was to assess the epidemiological features of children with craniosynostosis. This information includes the characteristics of the patients, their parents as well as their socioeconomic status.
Methods: This is a cross-sectional study performed from 2015 to 2020 in Imam Hossein Children's Hospital, Isfahan, Iran. We included 220 patients, under craniosynostosis treatment. A multidisciplinary team examined all participants. CT-scan was performed on all patients. All of the participants underwent surgical intervention. The recorded information was classified into four sections: characteristic data of children with craniosynostosis, Family history and parental information, including underlying diseases and drug history 3. Socioeconomic status 4. Treatment and surgery.
Results: 151 (68.7%) of participants were male and 171 (77.9%) had term delivery. The average birth weight was 2.92 kg and head circumference were 34.4 cm. the mean age of children at the time of surgery was 7.74 months and the mortality rate was 3 (1.4%). moreover, 90% were operated once and 10% were operated 2 or 3times. the most common type of craniosynostosis was Metopic 59 (59.4%). In relation to parenteral data, 96 (43.6%) of parents had consanguineous marriage and 6.4% had 1st and 2nd degree family with craniosynostosis.
Conclusion: Based on these findings, attention must be directed towards the potential risk of craniosynostosis in offspring born to consanguineous couples. Moreover, parents must receive guidelines for managing children affected by craniosynostosis.