Hospital Practices and Research

A Novel Strategy for Diabetes in the Armed Forces: Policy Justification for Integrating FTO Gene Screening into Nutritional Protocols to Manage Metabolic Risks

Articles in Press

Authors

Sobhan Mohammadi 1
Karim Parastouei 2

1 Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran

2 Department of Nutrition and Food Hygiene, Faculty of Health, Baqiyatallah University of Medical Sciences, Tehran, Iran

10.30491/hpr.2026.256772
Abstract
Type 2 diabetes is a growing global health issue, and military personnel are at increased risk due to unique stressors such as chronic occupational stress, disrupted sleep, and intense physical demands. These factors contribute to metabolic strain and raise the likelihood of developing the disease. Recent genetic studies highlight the role of the FTO gene, particularly the rs9939609 AA genotype, in increasing susceptibility to obesity and metabolic dysfunction. In military populations, individuals with this genotype show higher BMI, elevated fasting glucose, and increased LDL cholesterol, along with higher calorie and fat intake. These findings suggest the need for personalized health strategies that consider genetic predispositions. A one-size-fits-all approach is no longer sufficient. Instead, healthcare providers should tailor nutrition, exercise, and lifestyle recommendations based on individual genetic profiles to better manage metabolic risks. From a policy standpoint, military health systems should consider implementing genetic screening to identify high-risk personnel early. Targeted interventions, such as customized nutrition and fitness programs, should be prioritized for those with the AA genotype. Incorporating genomic data into long-term health monitoring can help track individual health trends and allow for early, proactive management of diabetes risk. Adopting these precision health strategies can reduce the prevalence of diabetes and related complications, improve force readiness, and lower long-term healthcare costs. Embracing genetic insights in military health policy can lead to more effective, individualized care and a stronger, healthier force.

Keywords

FTO gene
Type 2 Diabetes
Military Personnel
Nutrigenomics
Lipid Profile
Personalized Nutrition
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Hospital Practices and Research

Articles in Press, Accepted Manuscript
Available Online from 10 November 2026

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