Hospital Practices and Research

Public Health Policy: Garlic Powder as an Effective Supplement in the Management of Metabolic Syndrome and Fatty Liver

Articles in Press

Authors

Vahid Nazarpour 1
Mohammad Alizadeh 2, 3
Karim Parastouei 4
Abbasali Sanguni 4

1 Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran

2 Department of Nutrition, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran

3 Food and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran

4 Department of Nutrition and Food Hygiene, Faculty of Health, Baqiyatallah University of Medical Sciences, Tehran, Iran

10.30491/hpr.2026.256797
Abstract
Metabolic Syndrome (MetS) is a serious public health problem that significantly increases the risk of cardiovascular disease (CVD) and type 2 diabetes. This study aimed to determine the effectiveness of garlic powder supplementation in improving the components of MetS, fatty liver index, bowel function, and appetite control in affected patients. This study was a 12-week randomized, controlled, double-blind clinical trial involving 90 patients with MetS. Patients were divided into two groups: the intervention group receiving 1600 mg of garlic powder daily (in the form of four 400 mg tablets) and the control group receiving a placebo. After 12 weeks, the garlic powder group showed significant reductions in waist circumference, systolic and diastolic blood pressure, triglycerides, total cholesterol, and Fatty Liver Index (FLI) (P < 0.001). A significant improvement was also observed in HDL levels, appetite control, and bowel function. Changes in Body Mass Index (BMI) and fasting blood sugar were not statistically significant. Garlic powder supplementation can be used as a complementary and cost-effective nutritional strategy, alongside standard treatments, for managing risk factors associated with Metabolic Syndrome.

Keywords

Metabolic Syndrome
Garlic Powder Supplementation
Fatty Liver Index
Cardiovascular Risk Factors
Nutritional Intervention
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Hospital Practices and Research

Articles in Press, Accepted Manuscript
Available Online from 10 November 2026

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